Tirzepatide Once Weekly for the Treatment of Obesity
Ania M. Jastreboff, Louis J. Aronne, Nadia N. Ahmad, et al.; SURMOUNT-1 Investigators. New England Journal of Medicine. 2022.
Research published in the New England Journal of Medicine reported greater weight reduction with tirzepatide than placebo over 72 weeks in adults with obesity or overweight and a weight-related complication, without diabetes. Gastrointestinal adverse events were common, especially during dose escalation. This manufacturer-supported study did not compare tirzepatide with semaglutide, study Montana Trim Clinic patients, or establish compounded-product equivalence.
Read the original New England Journal of Medicine publication on PubMed